Cortisol verminderd NIET na post-wo suppletie [2002]

[Big T]

Effects of resistance exercise volume and nutritional supplementation on anabolic and catabolic hormones.

Williams AG, Ismail AN, Sharma A, Jones DA.

Human Physiology Research Group, School of Health, Staffordshire University, Stoke-on-Trent, UK. a.williams@staffs.ac.uk

Seven resistance-trained men performed six bouts of resistance exercise, each separated by at least 1 week, in a crossover design. High, moderate and low volumes of exercise were used, each performed twice and followed immediately post-exercise by either a placebo or carbohydrate-protein supplementation. All bouts of resistance exercise were performed using a load equal to 100% of each subject's ten-repetition maximum (10-RM), and all rest periods between sets of exercise were 1 min. Blood was obtained before and at intervals after exercise until 120 min post-exercise. Lactate levels were significantly (P < 0.05) elevated immediately post-exercise, and to a significantly greater extent after the greatest volume of exercise. Levels of growth hormone rose significantly after the greatest volume of exercise only. Those of insulin and glucose rose significantly after supplementation only. Cortisol levels tended to be higher after the greatest volume of exercise, but the differences were not significant. Supplementation had no effect on the lactate, growth hormone or cortisol responses to resistance exercise. The data indicate that volume of exercise and protein-carbohydrate supplementation can alter the metabolic and hormonal responses to resistance exercise independently. However, cortisol levels remain high after a high volume of resistance exercise, irrespective of whether a post-exercise carbohydrate-protein supplement is used.

In een andere studie is al bewezen dat ook vitamine C niets veranderd aan cortisol of het herstel bevorderd.

Dus het belang van maximaal 45 minuten training is weer maar eens aangetoond! (na 45 min piekt cortisol)

[mock]

Het grappige is dat ik ook heb gehoord dat je dus je koolhydraten voor je training moet nemen om je cortisol te drukken. Na de training neem je koolhydraten en eiwitten om je insuline piek extra te benutten. Alhoewel ik daar na een stukje van 3XL ook niet helemaal zeker van ben.

[Martinus]

Weet je of er studies zijn waaruit blijkt dat cortisol met andere middelen (7-keto, ginko, phosphatidylserine) wel gedrukt kan worden?

[B.B.Junkie]

Volgens mij zijn er ook tal van studies die aantonen dat P.W. voeding wel degelijk je cortisol aanmaak verminderd. Dat lijkt mij ook vrij logish omdat een flinke insuline stoot je zo uit de catabole toestand helpt.

[JimmyH]

Grote hoeveelheden (2000 to 4000 mg per dag) vitamine c helpt ook de cortisol te onderdrukken.(versrpreid over 2 keer innemen aangezien vitamine c maar 12 uur werkzaam is)

[wazzup]

allemaal leuke uitspraken, maar kunnen jullie die ook onderbouwen met (links naar) wetenschappelijke onderzoeken / artikelen ? Anders kan ik niet nagaan wat echte kennis is en wat "van die grote knul uit de sportschool" komt.

[B.B.Junkie]

Diet-hormone interactions: protein/carbohydrate ratio alters reciprocally the plasma levels of testosterone and cortisol and their respective binding globulins in man.

Anderson KE, Rosner W, Khan MS, New MI, Pang SY, Wissel PS, Kappas A.

The aim of this study was to determine if a change in protein/carbohydrate ratio influences plasma steroid hormone concentrations. There is little information about the effects of specific dietary components on steroid hormone metabolism in humans. Testosterone concentrations in seven normal men were consistently higher after ten days on a high carbohydrate diet (468 +/- 34 ng/dl, mean +/- S.E.) than during a high protein diet (371 +/- 23 ng/dl, p less than 0.05) and were accompanied by parallel changes in sex hormone binding globulin (32.5 +/- 2.8 nmol/l vs. 23.4 +/- 1.6 nmol/l respectively, p less than 0.01). By contrast, cortisol concentrations were consistently lower during the high carbohydrate diet than during the high protein diet (7.74 +/- 0.71 micrograms/dl vs. 10.6 +/- 0.4 micrograms/dl respectively, p less than 0.05), and there were parallel changes in corticosteroid binding globulin concentrations (635 +/- 60 nmol/l vs. 754 +/- 31 nmol/l respectively, p less than 0.05). The diets were equal in total calories and fat. These consistent and reciprocal changes suggest that the ratio of protein to carbohydrate in the human diet is an important regulatory factor for steroid hormone plasma levels and for liver-derived hormone binding proteins.

PMID: 3573976 [PubMed - indexed for MEDLINE]

Influence of insulin and contractile activity on muscle size and protein balance.

Goldberg AL.

Although the biochemical mechanism by which insulin and contractile activity affect protein turnover in muscle are still unclear, certain physiologic conclusions can be made; (a) Increased work can induce muscle hypertrophy even in the diabetic or starving animal. Thus, work-induced growth differs from normal growth of muscle in not requiring insulin. (b) Like insulin, repeated contractions stimulate the transport of amino acids into muscle. Contractile activity or passive tension can also reduce the rate of protein degradation in this tissue. These effects can be shown with isolated muscles in vitro, but the mechanisms coupling contractile activity to these anabolic processes are unknown. (c) Insulin also reduces overall protein breakdown in skeletal muscle, heart, and liver, apparently by regulating lysosomal function. (d) Insulin reduces selectively the breakdown of cell proteins with relatively long half-lives. This hormone does not affect the rapid breakdown of abnormal proteins which probably does not occur within the lysosome. (c) Normally, liver and muscle degrade large, acidic cell proteins quite rapidly, but this selectivity is lost in the tissues of diabetic or starved organisms, in which proteolysis is accelerated.

PMID: 761710 [PubMed - indexed for MEDLINE]

Het is logisch dat hoe langer en intensiever je traint, hoe meer cortisol je aanmaakt.
Goede P.W. voeding zorgt ervoor dat je de spierafbraak tot een minimum beperkt dus het heeft wel degelijk invloed op je resultaat.

Als ik wat meer tijd heb zal ik eens verder zoeken.

[B.B.Junkie]

Carbohydrate supplementation and perceived exertion during prolonged running.

Utter AC, Kang J, Nieman DC, Dumke CL, McAnulty SR, Vinci DM, McAnulty LS.

Department of Health, Leisure, and Exercise Science, Appalachian State University, Boone, NC, USA. utterac@appstate.edu

PURPOSE: The purpose of this study was to investigate the relationship between carbohydrate energy substrate and hormonal regulation on the perception of exertion during prolonged running. METHODS: Sixteen experienced marathoners ran on treadmills for 3 h at approximately 70% VO2max on two occasions while receiving 1 L x h carbohydrate (C) or placebo (P) beverages. Blood and vastus lateralis muscle biopsy samples were collected before and after exercise. RESULTS: The pattern of change in ratings of perceived exertion (RPE) over time was significantly different between C and P ingestion (P < 0.01) with attenuated RPE responses found in the latter part of the 3 h run. The pattern of change in the respiratory exchange ratio and carbohydrate oxidation rates were significantly greater (P < 0.01) in the C than P condition. Change in muscle glycogen content did not differ between C and P (P = 0.246). C relative to P ingestion was associated with higher plasma levels of glucose, insulin, and lactate and lower levels plasma cortisol. CONCLUSIONS: These data indicate that a lower RPE was associated with a higher carbohydrate oxidation, plasma glucose, and insulin levels, and lower plasma cortisol during prolonged running after C supplementation as compared with P feeding despite no differences in muscle glycogen content. These findings support a physiological link between RPE and carbohydrate substrate availability as well as selected hormonal regulation during prolonged running.

Publication Types:
• Clinical Trial
• Randomized Controlled Trial

PMID: 15179174 [PubMed - indexed for MEDLINE]

[B.B.Junkie]

Vitamin C supplementation attenuates the increases in circulating cortisol, adrenaline and anti-inflammatory polypeptides following ultramarathon running.

Peters EM, Anderson R, Nieman DC, Fickl H, Jogessar V.

Department of Physiology, Faculty of Medicine, University of Natal, Durban, South Africa. futree@med.und.ac.za

The effects of vitamin C supplementation on the alterations in the circulating concentrations of cortisol, adrenaline, interleukin-10 (IL-10) and interleukin-1 receptor antagonist (IL-1Ra) which accompany ultramarathon running were measured using immuno-chemiluminescence, radioimmunoassay and ELISA procedures. Forty-five participants in the 1999 Comrades 90 km marathon were divided into equal groups (n = 15) receiving 500 mg/day Vit C (VC-500), 1500 mg/day Vit C (VC-1500) or placebo (P) for 7 days before the race, on the day of the race, and for 2 days following completion. Runners recorded dietary intake before, during and after the race and provided 35 ml blood samples 15 - 18 hrs before the race, immediately post-race, 24 hrs post race and 48 hrs post-race. Twenty-nine runners (VC-1500, n = 12; VC-500, n = 10; P, n = 7) complied with all study requirements. All post-race concentrations were adjusted for plasma volume changes. Analyses of dietary intakes and blood glucose and anti-oxidant status on the day preceding the race and the day of the race did not reveal that carbohydrate intake or plasma vitamins E and A were significant confounders in the study. Mean pre-race concentrations of serum vitamin C in VC-500 and VC-1500 groups (128 +/- 31 and 153 +/- 34 micromol/l) were significantly higher than in the P group (83 +/- 39 micromol/l). Immediate post-race serum cortisol was significantly lower in the VC-1500 group (p < 0.05) than in P and VC-500 groups. When the data from VC-500 and P groups was combined (n = 17), immediate post-race plasma adrenaline, IL-10 and IL-1Ra concentrations were also significantly lower (p < 0.05) in the VC-1500 group. The study demonstrates an attenuation, albeit transient, of both the adrenal stress hormone and anti-inflammatory polypeptide response to prolonged exercise in runners who supplemented with 1500 mg vitamin C per day when compared to < or = 500 mg per day.
Publication Types:
Clinical Trial
Controlled Clinical Trial

PMID: 11590482 [PubMed - indexed for MEDLINE]

[B.B.Junkie]

Attenuation of increase in circulating cortisol and enhancement of the acute phase protein response in vitamin C-supplemented ultramarathoners.

Peters EM, Anderson R, Theron AJ.

School of Medical Sciences, Faculty of Medicine, University of Natal, Durban, South Africa.

Supplementary vitamin C (2 x 500 mg tablets daily) or a matched placebo was administered to 10 and 6 ultramarathon athletes respectively for 7 days prior to participation in a 90 kilometer running event, as well as on the day of the race and for 2 days after its completion. Circulating concentrations of vitamins A, C and E, as well as those of leukocytes and platelets, myeloperoxidase, C-reactive protein (CRP), interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF), cortisol, and creatine kinase were measured 16 hours before the race and at 30 min, 24 hours, and 48 hours after completion. Pre-race vitamin C concentrations in the supplemented group were unchanged after the race (118.2 +/- 15.9 and 115.9 +/- 11.9 micromol/l) while an increase was observed in the placebo group immediately post-race (85.8 +/- 11.9 to 107.4 +/- 18.8 micromol), with a return to pre-race values after 24 hours. Immediately on completion of the race transient elevations occurred in the concentrations of circulating neutrophils, monocytes and platelets, IL-6, cortisol, CRP, and creatine kinase in both groups. In the supplemented group the concentrations of CRP were significantly higher (p < 0.01) at each of the post-race time-points while those of cortisol were 30% lower immediately post-race. These observations provide evidence that supplementation with vitamin C may blunt the adaptive mobilization of this vitamin from the adrenals during exercise-induced oxidative stress and may be associated with an enhancement of the acute phase protein response and attenuation of the exercise-induced increase in serum cortisol.

Publication Types:
Clinical Trial
Randomized Controlled Trial

PMID: 11281614 [PubMed - indexed for MEDLINE]

[wazzup]

Ah, klasse,

Hieruit maak ik op, dat voor hardlopers die 1500 mg Vit-C nemen en voldoende KH in hun dagelijkse dieet (dus geen KETO-fan's) hebben hun "post-race-cortisol" niveaus aanzienlijk (30%) lager zijn. Ook KH tijdens het lopen van een marathon had en positieve werking.

En vitamine-C moet je niet POST, maar juist PRE workout nemen. (en niet vlak ervoor, maar ruim ervoor)

Maar al met al (even uitgezonderd het feit dat het hier om hardlopers ging) zie ik zo snel nog niet een weerlegging van Tijl's oorspronkelijke stelling dat POST-workout iets doet aan je cortisol... in tegendeel zelfs, ik geloof zelfs nog sterker nu dat als je de cortiosl wilt drukken je dit vooral VOOR je workout moet doen qua voeding).

[Big T]

Origineel gepost door B.B.Junkie

Diet-hormone interactions: protein/carbohydrate ratio alters reciprocally the plasma levels of testosterone and cortisol and their respective binding globulins in man.

Anderson KE, Rosner W, Khan MS, New MI, Pang SY, Wissel PS, Kappas A.

The aim of this study was to determine if a change in protein/carbohydrate ratio influences plasma steroid hormone concentrations. There is little information about the effects of specific dietary components on steroid hormone metabolism in humans. Testosterone concentrations in seven normal men were consistently higher after ten days on a high carbohydrate diet (468 +/- 34 ng/dl, mean +/- S.E.) than during a high protein diet (371 +/- 23 ng/dl, p less than 0.05) and were accompanied by parallel changes in sex hormone binding globulin (32.5 +/- 2.8 nmol/l vs. 23.4 +/- 1.6 nmol/l respectively, p less than 0.01). By contrast, cortisol concentrations were consistently lower during the high carbohydrate diet than during the high protein diet (7.74 +/- 0.71 micrograms/dl vs. 10.6 +/- 0.4 micrograms/dl respectively, p less than 0.05), and there were parallel changes in corticosteroid binding globulin concentrations (635 +/- 60 nmol/l vs. 754 +/- 31 nmol/l respectively, p less than 0.05). The diets were equal in total calories and fat. These consistent and reciprocal changes suggest that the ratio of protein to carbohydrate in the human diet is an important regulatory factor for steroid hormone plasma levels and for liver-derived hormone binding proteins.

PMID: 3573976 [PubMed - indexed for MEDLINE]

Influence of insulin and contractile activity on muscle size and protein balance.

Goldberg AL.

Although the biochemical mechanism by which insulin and contractile activity affect protein turnover in muscle are still unclear, certain physiologic conclusions can be made; (a) Increased work can induce muscle hypertrophy even in the diabetic or starving animal. Thus, work-induced growth differs from normal growth of muscle in not requiring insulin. (b) Like insulin, repeated contractions stimulate the transport of amino acids into muscle. Contractile activity or passive tension can also reduce the rate of protein degradation in this tissue. These effects can be shown with isolated muscles in vitro, but the mechanisms coupling contractile activity to these anabolic processes are unknown. (c) Insulin also reduces overall protein breakdown in skeletal muscle, heart, and liver, apparently by regulating lysosomal function. (d) Insulin reduces selectively the breakdown of cell proteins with relatively long half-lives. This hormone does not affect the rapid breakdown of abnormal proteins which probably does not occur within the lysosome. (c) Normally, liver and muscle degrade large, acidic cell proteins quite rapidly, but this selectivity is lost in the tissues of diabetic or starved organisms, in which proteolysis is accelerated.

PMID: 761710 [PubMed - indexed for MEDLINE]

Het is logisch dat hoe langer en intensiever je traint, hoe meer cortisol je aanmaakt.
Goede P.W. voeding zorgt ervoor dat je de spierafbraak tot een minimum beperkt dus het heeft wel degelijk invloed op je resultaat.

Als ik wat meer tijd heb zal ik eens verder zoeken.

Deze studies zeggen niets over post-WO suppletie en cortisol, de eerste gaat over hoog koolhydraat dieet, de tweede zegt niets over cortisol. Niet zo relevant in deze thread dus.

[Big T]

Origineel gepost door B.B.Junkie

Carbohydrate supplementation and perceived exertion during prolonged running.

Utter AC, Kang J, Nieman DC, Dumke CL, McAnulty SR, Vinci DM, McAnulty LS.

Department of Health, Leisure, and Exercise Science, Appalachian State University, Boone, NC, USA. utterac@appstate.edu

PURPOSE: The purpose of this study was to investigate the relationship between carbohydrate energy substrate and hormonal regulation on the perception of exertion during prolonged running. METHODS: Sixteen experienced marathoners ran on treadmills for 3 h at approximately 70% VO2max on two occasions while receiving 1 L x h carbohydrate (C) or placebo (P) beverages. Blood and vastus lateralis muscle biopsy samples were collected before and after exercise. RESULTS: The pattern of change in ratings of perceived exertion (RPE) over time was significantly different between C and P ingestion (P < 0.01) with attenuated RPE responses found in the latter part of the 3 h run. The pattern of change in the respiratory exchange ratio and carbohydrate oxidation rates were significantly greater (P < 0.01) in the C than P condition. Change in muscle glycogen content did not differ between C and P (P = 0.246). C relative to P ingestion was associated with higher plasma levels of glucose, insulin, and lactate and lower levels plasma cortisol. CONCLUSIONS: These data indicate that a lower RPE was associated with a higher carbohydrate oxidation, plasma glucose, and insulin levels, and lower plasma cortisol during prolonged running after C supplementation as compared with P feeding despite no differences in muscle glycogen content. These findings support a physiological link between RPE and carbohydrate substrate availability as well as selected hormonal regulation during prolonged running.

Publication Types:
• Clinical Trial
• Randomized Controlled Trial

PMID: 15179174 [PubMed - indexed for MEDLINE]

"prolonged running" hebben we weinig aan...

[Big T]

Origineel gepost door B.B.Junkie

Vitamin C supplementation attenuates the increases in circulating cortisol, adrenaline and anti-inflammatory polypeptides following ultramarathon running.

Peters EM, Anderson R, Nieman DC, Fickl H, Jogessar V.

Department of Physiology, Faculty of Medicine, University of Natal, Durban, South Africa. futree@med.und.ac.za

The effects of vitamin C supplementation on the alterations in the circulating concentrations of cortisol, adrenaline, interleukin-10 (IL-10) and interleukin-1 receptor antagonist (IL-1Ra) which accompany ultramarathon running were measured using immuno-chemiluminescence, radioimmunoassay and ELISA procedures. Forty-five participants in the 1999 Comrades 90 km marathon were divided into equal groups (n = 15) receiving 500 mg/day Vit C (VC-500), 1500 mg/day Vit C (VC-1500) or placebo (P) for 7 days before the race, on the day of the race, and for 2 days following completion. Runners recorded dietary intake before, during and after the race and provided 35 ml blood samples 15 - 18 hrs before the race, immediately post-race, 24 hrs post race and 48 hrs post-race. Twenty-nine runners (VC-1500, n = 12; VC-500, n = 10; P, n = 7) complied with all study requirements. All post-race concentrations were adjusted for plasma volume changes. Analyses of dietary intakes and blood glucose and anti-oxidant status on the day preceding the race and the day of the race did not reveal that carbohydrate intake or plasma vitamins E and A were significant confounders in the study. Mean pre-race concentrations of serum vitamin C in VC-500 and VC-1500 groups (128 +/- 31 and 153 +/- 34 micromol/l) were significantly higher than in the P group (83 +/- 39 micromol/l). Immediate post-race serum cortisol was significantly lower in the VC-1500 group (p < 0.05) than in P and VC-500 groups. When the data from VC-500 and P groups was combined (n = 17), immediate post-race plasma adrenaline, IL-10 and IL-1Ra concentrations were also significantly lower (p < 0.05) in the VC-1500 group. The study demonstrates an attenuation, albeit transient, of both the adrenal stress hormone and anti-inflammatory polypeptide response to prolonged exercise in runners who supplemented with 1500 mg vitamin C per day when compared to < or = 500 mg per day.
Publication Types:
Clinical Trial
Controlled Clinical Trial

PMID: 11590482 [PubMed - indexed for MEDLINE]

"ultramarathon running"

gaat hier niet over krachttraining, er is een studie gedaan waaruit blijkt dat vitamine c niets veranderd aan de weerstand en cortisol bij krachtatleten.

[Big T]

Origineel gepost door B.B.Junkie

Attenuation of increase in circulating cortisol and enhancement of the acute phase protein response in vitamin C-supplemented ultramarathoners.

Peters EM, Anderson R, Theron AJ.

School of Medical Sciences, Faculty of Medicine, University of Natal, Durban, South Africa.

Supplementary vitamin C (2 x 500 mg tablets daily) or a matched placebo was administered to 10 and 6 ultramarathon athletes respectively for 7 days prior to participation in a 90 kilometer running event, as well as on the day of the race and for 2 days after its completion. Circulating concentrations of vitamins A, C and E, as well as those of leukocytes and platelets, myeloperoxidase, C-reactive protein (CRP), interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF), cortisol, and creatine kinase were measured 16 hours before the race and at 30 min, 24 hours, and 48 hours after completion. Pre-race vitamin C concentrations in the supplemented group were unchanged after the race (118.2 +/- 15.9 and 115.9 +/- 11.9 micromol/l) while an increase was observed in the placebo group immediately post-race (85.8 +/- 11.9 to 107.4 +/- 18.8 micromol), with a return to pre-race values after 24 hours. Immediately on completion of the race transient elevations occurred in the concentrations of circulating neutrophils, monocytes and platelets, IL-6, cortisol, CRP, and creatine kinase in both groups. In the supplemented group the concentrations of CRP were significantly higher (p < 0.01) at each of the post-race time-points while those of cortisol were 30% lower immediately post-race. These observations provide evidence that supplementation with vitamin C may blunt the adaptive mobilization of this vitamin from the adrenals during exercise-induced oxidative stress and may be associated with an enhancement of the acute phase protein response and attenuation of the exercise-induced increase in serum cortisol.

Publication Types:
Clinical Trial
Randomized Controlled Trial

PMID: 11281614 [PubMed - indexed for MEDLINE]

Ook deze studie zegt niets nieuws en bewijst nog steeds niet dat krachtatleten voordeel hebben aan pre -of postWO suppletie om cortisol afgifte te verminderen.

REVIEW:

Vitamin C: effects of exercise and requirements with training.

Peake JM.

School of Human Movement Studies at the University of Queensland, St Lucia, QLD 4072, Australia.

Ascorbic acid or vitamin C is involved in a number of biochemical pathways that are important to exercise metabolism and the health of exercising individuals. This review reports the results of studies investigating the requirement for vitamin C with exercise on the basis of dietary vitamin C intakes, the response to supplementation and alterations in plasma, serum, and leukocyte ascorbic acid concentration following both acute exercise and regular training. The possible physiological significance of changes in ascorbic acid with exercise is also addressed. Exercise generally causes a transient increase in circulating ascorbic acid in the hours following exercise, but a decline below pre-exercise levels occurs in the days after prolonged exercise. These changes could be associated with increased exercise-induced oxidative stress. On the basis of alterations in the concentration of ascorbic acid within the blood, it remains unclear if regular exercise increases the metabolism of vitamin C. However, the similar dietary intakes and responses to supplementation between athletes and nonathletes suggest that regular exercise does not increase the requirement for vitamin C in athletes. Two novel hypotheses are put forward to explain recent findings of attenuated levels of cortisol postexercise following supplementation with high doses of vitamin C.

The role of ascorbic acid and xylitol in etomidate-induced adrenocortical suppression in humans.

Schraag S, Pawlik M, Mohl U, Bohm BO, Georgieff M.

Clinic of Anaesthesiology, University of Ulm Medical School, Germany.

Etomidate-induced suppression of cortisol biosynthesis is a result of a blockade of 11-beta-hydroxylation in the adrenal gland, mediated by the imidazol radical of etomidate. Since the generation of steroids requires reductive and energy rich equivalents, the present study examined whether supplementation with ascorbic acid or xylitol, a major source of NADPH, could attenuate adrenal suppression by etomidate in human subjects by promoting the turnover rate of 11-beta-hydroxylase. During continuous etomidate/alfentanil anaesthesia for pelviscopic surgery 30 female patients received either Ringer's lactate, xylitol (0.25 g kg-1 h-1) or ascorbic acid (0.5 g h-1) intravenously (i.v.). The plasma concentrations of cortisol, aldosterone and dehydroepiandrosterone (DHEA) were recorded for 5 h after end of surgery and a stimulation with synthetic ACTH was performed. The results showed no evidence of a clinically relevant attenuating effect of ascorbic acid or xylitol on etomidate-induced adrenocortical suppression. However, the observed suppression of cortisol levels was not enough to allow an attenuating affect to be measured

Effects of ascorbic acid and carbohydrate ingestion on exercise induced oxidative stress.

Vasankari T, Kujala U, Sarna S, Ahotupa M.

Department of Physiology, University of Turku, Finland.

BACKGROUND: We studied the effects of supplementation of vitamin C and carbohydrate on acute exercise-induced lipid peroxidation. METHODS: Experimental design: two randomized controlled trials. PARTICIPANTS: 17 endurance athletes. Interventions: in study I, nine athletes repeated twice a 10.5-km maximal run and ingested in a randomized single-blind order either 2.0 g vitamin C or placebo. In study II, eight athletes repeated twice a 27-km maximal run and ingested in randomly either 105 g carbohydrate or placebo. Venous blood samples were taken before the exercise, immediately after the exercise, and after a recovery period of 90 min (study I) or 120 min (study II). Measure: serum diene conjugation, lipid peroxidation. RESULTS: In study I, there was no difference in serum diene conjugation between the trials during exercise (pre- vs post-exercise). However, during the recovery period (post-exercise vs recovery sample) serum diene conjugation concentration decreased by 11% in the vitamin C trial but not in placebo (p = 0.028). In study II, there was no difference between the carbohydrate and placebo trials. CONCLUSIONS: Vitamin C and carbohydrate do not prevent exercise-induced increase in oxidative stress

Zijn er nog maar vind ze ff niet.

[Big T]

Origineel gepost door wazzup

Ah, klasse,

Hieruit maak ik op, dat voor hardlopers die 1500 mg Vit-C nemen en voldoende KH in hun dagelijkse dieet (dus geen KETO-fan's) hebben hun "post-race-cortisol" niveaus aanzienlijk (30%) lager zijn. Ook KH tijdens het lopen van een marathon had en positieve werking.

En vitamine-C moet je niet POST, maar juist PRE workout nemen. (en niet vlak ervoor, maar ruim ervoor)

Maar al met al (even uitgezonderd het feit dat het hier om hardlopers ging) zie ik zo snel nog niet een weerlegging van Tijl's oorspronkelijke stelling dat POST-workout iets doet aan je cortisol... in tegendeel zelfs, ik geloof zelfs nog sterker nu dat als je de cortiosl wilt drukken je dit vooral VOOR je workout moet doen qua voeding).

Wat je ook doet pre training, cortisol zal altijd stijgen. Bij krachttraining krijg je sneller een piek terwijl het bij duursporten meer geleidelijk gaat. Je kan, zo blijkt uit studies, dit proces niet tegenhouden of verminderen, het enige wat je kan doen is tijdig stoppen met de training en zorgen dat pre -en post wo voeding optimaal is. (Vooral pre wo suppletie blijkt steeds belangrijker te worden)

[RendezVous]

beetje offtopic..

Waarom zou je de cortisol waarde willen laten dalen?

Mijn lichaam maakt geen cortisol meer aan en ik krijg dus ook cortisol tableltten. Als ik ze vergeet in te nemen wordt ik goed ziek. Na intensief sporten (vooral buikspieren) wordt ik dan ook goed misselijk, waarschijnlijk door een tekort aan cortisol waar me lichaam toch om vraagt!

De endocrinoloog heeft me verteld dat cortisol toch echt nodig is om je smorgens wakker en actief te krijgen en dit zal ook wel het geval zijn bij het sporten..

[Big T]

Er is een verschil tussen een tekort en een teveel, soms wil je liever dat het wat lager is, dat is daarom niet ongezond, maar wel positief voor je spieren.

Bijvoorbeeld na krachttraining stijgt cortisol omdat je lichaam denkt dat het snel energie nodig heeft, maar eigenlijk is dat niet zo want je gaat daarna toch wel eten. Maar dat weet je lichaam niet. Door je cortisol laag te houden op dat moment spaar je spiereiwit...

[Frenkpie]

Maar kan rendezvous dus nu langer trainen omdat zn lichaam niet of bijna geen cortisol aanmaakt?

[Big T]

Hij zegt zelf misselijk te worden na een lange training. Of je nu te weinig of te veel cortisol in je bloed hebt het is beiden slecht. Dus langdurig KT doen is altijd nadelig imo.