Effects of HMB on exercise performance and body composition

**3XL** · 7 January 2008, 19:00

Effects of beta-hydroxy-beta-methylbutyrate (HMB) on exercise performance and body composition across varying levels of age, sex, and training experience: A review

http://www.nutritionandmetabolism.co...3-7075-5-1.pdf

Pietje1983 · 7 January 2008, 19:09

kun je er misschien een ander tekstbestandje van maken? kheb geen acrobat reader...

alvast bedankt!

black2white · 7 January 2008, 19:31

----------------------------------------------------------
Conclusions
The first purpose of this paper was to provide an in depth and objective analysis of HMB
research. While various studies analyzed in this manuscript support the efficacy of HMB as an
effective ergogenic aid for athletes that decreases DOMS, markers of muscle damage, and body
fat, while increasing various markers of performance, including LBM and strength in resistance
trained athletes, and OBLA and VO2 peak in endurance trained athletes, a number of studies
analyzed did not support the efficacy of HMB supplementation. The current authors suggest that
these conflicting results may in part be attributed to the variability in humans, inadequate sample
sizes, and methodological issues such as the specificity of testing conditions, cases of
overtraining, elicitation of an inadequate training stimulus in experienced participants, limited
dependent variables, and short duration experiments. Collectively, these results warrant further
research on HMB supplementation while taking into account these various issues. Tables 1 and 2
summarize the results from the HMB literature.
There is compelling evidence that HMB supplementation may be useful for clinical
muscle wasting conditions including AIDS, cancer, bed-rest, and during periods of caloric
deficits. HMB also appears to be safe, and may improve various markers of health, including
blood pressure and LDL-cholesterol. When supplementing with HMB, current evidence suggests
that 1 g of HMB should be consumed 3 times per day, for a total of 3 g of HMB daily (or 38
mg/kg of bodyweight) .However, more studies are needed to determine the optimal dosage and frequency of HMB supplementation, and the overall efficacy of HMB supplementation as an
ergogenic aid for athletes.
The second purpose of this paper was to provide an in depth analysis of possible
mechanisms that HMB may exert its effects. Results from this review showed that HMB appears to primarily exert its effects through protective and anticatabolic mechanism. The prevailing
explanation is the cholesterol synthesis hypothesis. However, recent studies have shown that
HMB’s anticatabolic effects are at least in part mediated by attenuation of the activation and
increased gene expression of the ubiquitin-pathway. Furthermore, there is evidence that HMB
may directly increase protein synthesis.
-------------------------------------------------

dat is ff de conclusie, miss handig voor de snelle lezers

**3XL** · 7 January 2008, 19:31

Ik denk dat als je jezelf op de hoogte wilt houden van onderzoeken je beter (gratis) een reader kan downloaden.

Veel van dit soort onderzoeken word namenlijk als pdf geplaatst.

Pietje1983 · 7 January 2008, 19:34

@black2white: thanks

@3XL: ook bedankt, ga er eentje van het internet plunderen..

j3330 · 7 January 2008, 19:40

dus eigenlijk komt het erop neer dat effectief is als cutsupplement en vooral in extreme stresstoestand en verder ook dathet proteine synthesis verhoogt.
Dat was wat men reeds vermoedde toch?
Eindelijk wel eens bewezen in een serieus artikel.

@pietje: neem gewoon adobe reader.

hypnotizedman · 5 February 2008, 14:25

@xxl: mooi. Bedankt

**maniac** · 5 February 2008, 14:55

K*t, heeft Brutez toch gelijk!

Brutez · 8 February 2008, 10:13

Haha

Robke78 · 8 February 2008, 10:17

wat is dat toch maar met die HMB

Ja, nee, ja, nee, ja, nee ... make up your mind allready

Pietje1983 · 8 February 2008, 14:30

mooi topic van 3XL, MAAR, ik denk nog steeds dat HMB wél degelijk nut heeft.. er zijn nl. meer onderzoeken geweest, waarin HMB datgene doet wat het beloofd.

**TheNose** · 8 February 2008, 15:14

Citaat:

Origineel gepost door Pietje1983

mooi topic van 3XL, MAAR, ik denk nog steeds dat HMB wél degelijk nut heeft.. er zijn nl. meer onderzoeken geweest, waarin HMB datgene doet wat het beloofd.

Ehm waarom de maar? Dat is toch ook de conclusie van het hele onderzoek?

Pietje1983 · 8 February 2008, 15:21

heuh kwas ff nie bij de les

nachtdiensten zullen we maar zeggen..

**Big T** · 9 February 2008, 08:13

Citaat:

Origineel gepost door maniac

K*t, heeft Brutez toch gelijk!

Deze review zegt helemaal niet dat HMB 'werkt' (met werken bedoel ik extra spiergroei stimuleerd).

Het zegt alleen wat over de anti-catabole werking, en enkele andere effecten mbt de gezondheid. Tot nu toe is een werking alleen bij of dieren, of beginnende sporters vastgesteld als ik me niet vergis. De twijfelachtige effecten van HMB verantwoorden in elk geval niet de aankoop en dus zou ik het echt niet aanraden, er zijn anderen supplementen die je geld meer waard zijn.

Dit onderzoek zegt genoeg: HMB: nieuw onderzoek bevestigd negatieve resultaten [2004]

Marky · 9 February 2008, 23:33

HMB. Hoogst Mogelijke Bedrieging

7 January 2008, 19:00	#1
3XL Super Moderator Geregistreerd: Apr 2002 Locatie: افغانستان Geslacht: V Posts: 11.142 Casino cash: €19850 Karma Power: 29	Effects of HMB on exercise performance and body composition Effects of beta-hydroxy-beta-methylbutyrate (HMB) on exercise performance and body composition across varying levels of age, sex, and training experience: A review http://www.nutritionandmetabolism.co...3-7075-5-1.pdf __________________ As you are now, I once was. As I am now, you'll never be ©3XL ®2000 The only easy day was yesterday...............Life is hard, so am I Geloof niets, probeer alles

7 January 2008, 19:09	#2
Pietje1983 Ripped Bodybuilder Geregistreerd: Dec 2007 Locatie: Voor de spiegel, bij het dumbbellrek... Geilen op adertjes enzo ;) jwtz Leeftijd: 24 Geslacht: M Posts: 4.469 Casino cash: €27250 Karma Power: 18	Re: Effects of HMB on exercise performance and body composition kun je er misschien een ander tekstbestandje van maken? kheb geen acrobat reader... alvast bedankt! __________________ Animal M-Stak... The "M" Stands for Mass. Current stop: Dorian Yates - Ultimate NOX Pump Formula & Labrada - Super Charge! Nitric Oxide Next stop: Alri - WTF Pump'd This game, this iron warfare... Shit, it's all about progress and conquest. I'm here to tell you the real life begins when you're in the weight room.. So be prepared to get your hands dirty.

7 January 2008, 19:31	#3
black2white Cool Novice Geregistreerd: Dec 2007 Locatie: Nederland Leeftijd: 21 Geslacht: V Posts: 215 Casino cash: €15644 Karma Power: 1	Re: Effects of HMB on exercise performance and body composition ---------------------------------------------------------- Conclusions The first purpose of this paper was to provide an in depth and objective analysis of HMB research. While various studies analyzed in this manuscript support the efficacy of HMB as an effective ergogenic aid for athletes that decreases DOMS, markers of muscle damage, and body fat, while increasing various markers of performance, including LBM and strength in resistance trained athletes, and OBLA and VO2 peak in endurance trained athletes, a number of studies analyzed did not support the efficacy of HMB supplementation. The current authors suggest that these conflicting results may in part be attributed to the variability in humans, inadequate sample sizes, and methodological issues such as the specificity of testing conditions, cases of overtraining, elicitation of an inadequate training stimulus in experienced participants, limited dependent variables, and short duration experiments. Collectively, these results warrant further research on HMB supplementation while taking into account these various issues. Tables 1 and 2 summarize the results from the HMB literature. There is compelling evidence that HMB supplementation may be useful for clinical muscle wasting conditions including AIDS, cancer, bed-rest, and during periods of caloric deficits. HMB also appears to be safe, and may improve various markers of health, including blood pressure and LDL-cholesterol. When supplementing with HMB, current evidence suggests that 1 g of HMB should be consumed 3 times per day, for a total of 3 g of HMB daily (or 38 mg/kg of bodyweight) .However, more studies are needed to determine the optimal dosage and frequency of HMB supplementation, and the overall efficacy of HMB supplementation as an ergogenic aid for athletes. The second purpose of this paper was to provide an in depth analysis of possible mechanisms that HMB may exert its effects. Results from this review showed that HMB appears to primarily exert its effects through protective and anticatabolic mechanism. The prevailing explanation is the cholesterol synthesis hypothesis. However, recent studies have shown that HMB’s anticatabolic effects are at least in part mediated by attenuation of the activation and increased gene expression of the ubiquitin-pathway. Furthermore, there is evidence that HMB may directly increase protein synthesis. ------------------------------------------------- dat is ff de conclusie, miss handig voor de snelle lezers __________________ _~~>>>> It is the feeling that gives the drive to perform even harder! <<<<~~_

7 January 2008, 19:31	#4
3XL Super Moderator Geregistreerd: Apr 2002 Locatie: افغانستان Geslacht: V Posts: 11.142 Casino cash: €19850 Karma Power: 29	Re: Effects of HMB on exercise performance and body composition Ik denk dat als je jezelf op de hoogte wilt houden van onderzoeken je beter (gratis) een reader kan downloaden. Veel van dit soort onderzoeken word namenlijk als pdf geplaatst. __________________ As you are now, I once was. As I am now, you'll never be ©3XL ®2000 The only easy day was yesterday...............Life is hard, so am I Geloof niets, probeer alles

7 January 2008, 19:34	#5
Pietje1983 Ripped Bodybuilder Geregistreerd: Dec 2007 Locatie: Voor de spiegel, bij het dumbbellrek... Geilen op adertjes enzo ;) jwtz Leeftijd: 24 Geslacht: M Posts: 4.469 Casino cash: €27250 Karma Power: 18	Re: Effects of HMB on exercise performance and body composition @black2white: thanks @3XL: ook bedankt, ga er eentje van het internet plunderen.. __________________ Animal M-Stak... The "M" Stands for Mass. Current stop: Dorian Yates - Ultimate NOX Pump Formula & Labrada - Super Charge! Nitric Oxide Next stop: Alri - WTF Pump'd This game, this iron warfare... Shit, it's all about progress and conquest. I'm here to tell you the real life begins when you're in the weight room.. So be prepared to get your hands dirty.

7 January 2008, 19:40	#6
j3330 Competitive Bodybuilder Geregistreerd: Jan 2006 Locatie: België Geslacht: M Posts: 2.159 Casino cash: €24082 Karma Power: 11	Re: Effects of HMB on exercise performance and body composition dus eigenlijk komt het erop neer dat effectief is als cutsupplement en vooral in extreme stresstoestand en verder ook dathet proteine synthesis verhoogt. Dat was wat men reeds vermoedde toch? Eindelijk wel eens bewezen in een serieus artikel. @pietje: neem gewoon adobe reader.

5 February 2008, 14:25	#7
hypnotizedman Cool Novice Geregistreerd: Apr 2006 Locatie: België Geslacht: M Posts: 100 Casino cash: €450 Karma Power: 3	Re: Effects of HMB on exercise performance and body composition @xxl: mooi. Bedankt

5 February 2008, 14:55	#8
maniac Puny human Geregistreerd: Nov 2002 Locatie: Titty Twister Geslacht: M Posts: 6.460 Casino cash: €16850 Karma Power: 60	Re: Effects of HMB on exercise performance and body composition Kt, heeft Brutez toch gelijk! __________________ Pimpin' Iron* *"Religion is regarded by the common people as true, by the wise as false, and by the rulers as useful"*

8 February 2008, 10:13	#9
Brutez Huge Freak Geregistreerd: Jan 2004 Locatie: Nederland Leeftijd: 26 Geslacht: M Posts: 7.018 Casino cash: €27650 Karma Power: 47	Re: Effects of HMB on exercise performance and body composition Haha __________________ I went to the gym to workout.. but it didn’t work out..

8 February 2008, 10:17	#10
Robke78 Freaky Bodybuilder Geregistreerd: Dec 2006 Locatie: Limburg BE Leeftijd: 30 Geslacht: M Posts: 6.545 Casino cash: €13845 Blog Berichten: 5 Karma Power: 55	Re: Effects of HMB on exercise performance and body composition wat is dat toch maar met die HMB Ja, nee, ja, nee, ja, nee ... make up your mind allready __________________ stop confusing me with your theoretical mumbojumbo - I use the calories from alcohol to stay out of starvation mode - Just drinks, foods ands lots of boinky boinky

8 February 2008, 14:30	#11
Pietje1983 Ripped Bodybuilder Geregistreerd: Dec 2007 Locatie: Voor de spiegel, bij het dumbbellrek... Geilen op adertjes enzo ;) jwtz Leeftijd: 24 Geslacht: M Posts: 4.469 Casino cash: €27250 Karma Power: 18	Re: Effects of HMB on exercise performance and body composition mooi topic van 3XL, MAAR, ik denk nog steeds dat HMB wél degelijk nut heeft.. er zijn nl. meer onderzoeken geweest, waarin HMB datgene doet wat het beloofd. __________________ Animal M-Stak... The "M" Stands for Mass. Current stop: Dorian Yates - Ultimate NOX Pump Formula & Labrada - Super Charge! Nitric Oxide Next stop: Alri - WTF Pump'd This game, this iron warfare... Shit, it's all about progress and conquest. I'm here to tell you the real life begins when you're in the weight room.. So be prepared to get your hands dirty.

8 February 2008, 15:21	#13
Pietje1983 Ripped Bodybuilder Geregistreerd: Dec 2007 Locatie: Voor de spiegel, bij het dumbbellrek... Geilen op adertjes enzo ;) jwtz Leeftijd: 24 Geslacht: M Posts: 4.469 Casino cash: €27250 Karma Power: 18	Re: Effects of HMB on exercise performance and body composition heuh kwas ff nie bij de les nachtdiensten zullen we maar zeggen.. __________________ Animal M-Stak... The "M" Stands for Mass. Current stop: Dorian Yates - Ultimate NOX Pump Formula & Labrada - Super Charge! Nitric Oxide Next stop: Alri - WTF Pump'd This game, this iron warfare... Shit, it's all about progress and conquest. I'm here to tell you the real life begins when you're in the weight room.. So be prepared to get your hands dirty.

9 February 2008, 23:33	#15
Marky Huge Freak Geregistreerd: Jun 2003 Locatie: Leeftijd: 17 Geslacht: M Posts: 8.663 Casino cash: €26159 Karma Power: 57	Re: Effects of HMB on exercise performance and body composition HMB. Hoogst Mogelijke Bedrieging __________________ DBC01 - Toonbeeld van gezondheid

Topic Opties	Zoek in Topic
Topic afdrukken Deze pagina e-mailen	Zoek in Topic: Uitgebreid Zoeken
Weergave Modus
Lineare Modus Verander naar Hybrid Mode Verander naar Threaded Mode